Fracture

Trabecular Bone Score and the Quest to Predict Who Will Fracture

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Each year 178 million new osteoporotic fractures occur worldwide. These fractures are painful, costly, and at times life-limiting. In the hope of preventing these fractures, medical systems around the world have looked for ways to identify those at greatest fracture risk. In Traditional Chinese Medicine the kidney energy meridian system is evaluated, as this is … Read more

Prolia for Bone Fractures — I’m Still Not Impressed

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When the bone drug Prolia (denosumab) first came out in 2010, I took a hard look at it because it used a completely different mechanism than widely used bisphosphonate drugs, focusing on the RANK/RANK-L/OPG system to prevent osteoclasts from being “activated” instead of decreasing their number like bisphosphonates. I wasn’t satisfied in 2010 that this … Read more